Questions About PD
yes, you are right. But why is your patient on 60 cycles of PD? The dosing is based on pharmacokinetic studies on CAPD rather than very rapid cycles. There is an adjustment of 25% increase in dosing if patients have significant RRF. If you increases the dosing, your patient may be at risk of drug toxicity. If a drug has a very high safety therapeutic margin, you may cautiously try increasing the dosage if you think your patient need higher dosage for effect, but obviously, you need to monitor the side effect more closely. checking drug level if available is recommended.