Questions About PD
To my knowledge, I have not seen anything in the literature that clearly examines this question. In general we say to continue peritoneal dialysis through peritonitis with IP antibiotics. I am not sure that antibiotics can be instilled in IPN for the dwell that is required for antibiotic administration due to compatibility issues (protein binding?). I think you would need to clarify this with the IPN vendor or pharmacy. I would suggest it would be best to use a dextrose based or icodextrin solution for the dwell required with the antibiotics. Otherwise, I would think that IPN would not be contraindicated when there is no antibiotics present since the risk of bacterial grown in dextrose would be no less.