Not at all. In a recent ANZDATA Registry study of 503 cases of S. aureus peritonitis, catheter removal was necessary in only a minority (23%) of episodes of MRSA peritonitis and was not significantly different from that of MSSA peritonitis (21%). As with other forms of peritonitis, catheter removal is indicated for refractory peritonitis (ie evidence of persistent peritonitis after 5 days of appropriate antibiotics). In the case of MRSA peritonitis, catheter removal is appreciably more likely if there is a concomitant exit site infection and is almost invariable if there is a concomitant tunnel infection.