Questions About PD
We thank you for your question. The average ultrafiltration (UF) rate when a patient uses a 4.25% PD solution can be as much as 300 cc to 400 cc/hour at the beginning of the dwell, but will decrease as glucose is absorbed across the peritoneal membrane. A patient who has high transport characteristics on the PET will have a lower UF rate, a patient who has low transport characteristics on the PET will have a higher UF rate. Today, regular use of a 4.25% PD solution is not recommended for management of a patient’s fluid volume for the following reasons: may adversely affect the peritoneal membrane function; will cause increased glucose absorption leading to worsening control of blood sugars; and will promote obesity. Instead, patients should be counselled, by a dietician if available, to decrease their fluid and salt intake.
Reference: Daugirdas, J.T., Blake, P.G. and Todd. S. (2015). Handbook of Dialysis, 5th edition. Philadelphia: Wolters Klewer.