Dear colleagues, Any of you had an ESRD patient on peritoneal dialysis trated with cisplatin? If so, what dose adjustment did you use? I have reviewed the scant literature available, but would not minde any anecdotal or unpublished observation you could share with me. Thank you very much. Lavinia Negrea, Nephrologist
Dear colleagues, Any of you had an ESRD patient on peritoneal dialysis trated with cisplatin? If so, what dose adjustment did you use? I have reviewed the scant literature available, but would not minde any anecdotal or unpublished observation you could share with me. Thank you very much. Lavinia Negrea, Nephrologist
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Lavinia N., Doctor/MD from cleveland, ohio asked
Dear colleagues, Any of you had an ESRD patient on peritoneal dialysis trated with cisplatin? If so, what dose adjustment did you use? I have reviewed the scant literature available, but would not minde any anecdotal or unpublished observation you could share with me. Thank you very much. Lavinia Negrea, Nephrologist

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⋅ ⋅ February 26, 2011

I don’t have any experience with cisplatin in PD patients but i can suggest you the following reference which recommends to Administer 50% of dose to CAPD patients.

Aronoff GR, Bennett WM, Berns JS, et al, Drug Prescribing in Renal Failure: Dosing Guidelines for Adults and Children, 5th ed. Philadelphia, PA: American College of Physicians; 2007, p 97, 170

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