Can Sodium Thiosulfate be used in the PD fluid to attempt to treat calciphlaxis

Questions About PD

resolved
Public
Jolyne S, Nurse asked
Can Sodium Thiosulfate be used in the PD fluid to attempt to treat calciphlaxis

1 answer

I am not aware of any reports of intraperitoneal sodium thiosulfate.Its molecular weight is 248 and so it is a bit more than twice the size of creatinine. So, in a four hour dwell in a person with an average transport type, half the intraperitoneally administered dose is anticipated to be absorbed. But there is another issue that is not tested – does it cause peritoneal inflammation if administered as twice the iv dose – that would be needed if administered intraperitoneally? With that, I would suggest that you limit to using iv dose described for HD

#1

Please login to submit an answer