Questions About PD
We thank you for your very interesting question. Different countries may have different guidelines from their dialysis solution providers. In general, PD solutions should be stored in the same box they arrive in, not below 4 degrees Celsius to avoid freezing and not above 30 degrees Celsius for long periods to avoid possible formation of glucose degradation products (1,2).
One recommendation from a nurse in the UK, if solutions are stored in an outside shed or garage and the weather is very cold, is to advise patients to bring their solutions inside the house two days before the solutions are to be used.
Please also note that very cold weather can have an effect on the cassettes used in automated peritoneal dialysis (APD) (become less pliable and will cause priming problems). If the weather is very cold and these are stored in a shed or garage, the recommendation for patients is also to bring these inside the house ahead of use, or place on the warmer area of the APD machine before setting up the APD machine.
1.Kjellstrand P, Erixon M, Wieslander A, Lindén T, Martinson E. Temperature: the single most important factor for degradation of glucose fluids during storage. Peritoneal Dialysis International. 2004 Jul; 24(4): 385-391.
2.electronic medicines compendium (emc). Dianeal PD4 Glucose 1.36% w/v 13.6 mg/ml https://www.medicines.org.uk/emc/product/1816/smpc Accessed April 8, 2022.