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Amy O
from USA asked on May 21, 2014:

Are there any studies that show a relationship between the incidence of peritonitis and whether a patient has a dry day or last fill? Thank you.


, from Europe ():
There are some old data based on few patients suggesting that a dry day may improve host defence and, therefore, improve peritonitis rates. However, in practice there is no important difference in risk of infection - neither between CAPD and APD, nor between NIPD and CCPD. It seems to be much more important that patients have adequate dialysis. Compared with NIPD (dry day) CCPD (last fill) is associated with better middle molecule clearances and sodium removal (at least when icodextrin is used for the last fill). Besides this other prophylactic measures could be considered if peritonitis rate is high (e.g. mupirocin prophylaxis at the exit site, intensified training and re-training of patients,...etc).

Disclaimer: The answers represent personal views of the experts. The readers should use their own discretion in interpretation and application of the answers and the ISPD does not hold liability for such usage.

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